منابع مشابه
Intracellular trafficking of porphyrins.
Hemes are porphyrins that play a critical role in diverse biological processes. Heme synthesis culminates in the mitochondrial matrix, but the eight-step biosynthetic pathway is spatially shared between the mitochondria and cytoplasm. A recent paper describes the nature of the transporter that translocates the heme precursor coproporphyrinogen III into the mitochondria for heme synthesis. The i...
متن کاملPorphyrins and Metalloporphyrins
This is another of an increasing number of human gross anatomy books being published in abbreviated form. Throughout the book each left-hand page contains quite accurate written descriptions of structures that are illustrated as line drawings on the opposite right-hand page. Even though the text is written in a telegraphic style and the drawings are small, the book still contains 443 pages. It ...
متن کاملStacked antiaromatic porphyrins
Aromaticity is a key concept in organic chemistry. Even though this concept has already been theoretically extrapolated to three dimensions, it usually still remains restricted to planar molecules in organic chemistry textbooks. Stacking of antiaromatic π-systems has been proposed to induce three-dimensional aromaticity as a result of strong frontier orbital interactions. However, experimental ...
متن کاملUrinary Porphyrins in Disease
The structural chemistry of the blood and bile pigments has been developed by Hans Fischer and his school (l), but the physiological conditions which lead to the increased production of these pigments, especially of the porphyrins, are still uncertain. Although it is well known that in many diseases, notably those characterized by fever or liver injury (2), an increased excretion of porphyrins ...
متن کاملOxidation of ferric porphyrins.
Characterization of heme oxidation products falls naturally into two categories: species resulting from electron transfer, and in vivo and in vitro heme degradation products formed by oxidative addition or cleavage. In the former, we propose to include the intermediates appearing during the catalytic cycles of catalase (Cat), horseradish peroxidase (HRP), and cytochrome c peroxidase; the latter...
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ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/260375b0